Texas medical marijuana regulations now permit access through the expanded Compassionate Use Program (TCUP), following the enactment of House Bill 46, which was signed into law on June 21, 2025, and is scheduled to take effect on September 1, 2025. This legislation expands the list of qualifying conditions by including chronic pain, Crohn’s disease, traumatic brain injury, terminal illness, and hospice care, in addition to the existing qualifiers such as epilepsy, cancer, ALS, autism, MS, PTSD, seizure disorders, and incurable neurodegenerative diseases. The new law replaces the previous 1% THC weight limit with a specific dosage cap of 10 mg THC per dose (1 g per package), introduces new delivery methods such as lotions, patches, suppositories, and non-smoked inhalation options (including nebulizers, vaporizers, and inhalers), and increases the number of licensed dispensing organizations from 3 to 15, along with satellite locations. Physicians are authorized to provide recommendations valid for up to one year, with four 90-day refills monitored through the Compassionate Use Registry, thereby ensuring regulated access for eligible patients in Texas.